Plasma PK profiles for Drug A                              
  i.v.bolus  
  mins [A] (ng/mL)  
  0  
  1  
  5  
  10  
  15  
  20  
  30  
  45  
  60  
  90  
  120  
     
         
For a 
Default: 200g
 g rat  
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i.v. bolus   Series1 Series2 Series3 Series4
Dose mg
  mg/kg
Default: 5mg/kg
C0 = ng/mL
t1/2 = mins
Vd L
Default: 0.1 L
  L/kg
k per min
Default: 0.1 per min
  per hr
Cl = L/min
  L/hr
 
 
  PK profiles for Drug B                    
  i.v.infusion  
  Duration = mins  
  mins [B] (ng/mL)  
  0  
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
       
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For a 
Default: 200g
 g rat  
i.v. infusion Series1 Series2 Series3 Series4
Dose mg/kg/hr
Default: 5mg/kg/hr
  mg/hr
  mg/min
t1/2 = hr
  min
Vd L
Default: 0.1 L
  L/kg
k per min
Default: 0.1 per min
  per hr
Cl = L/min
  L/hr
 
  PK profiles for Drug C                      
  hr Oral dose  
  [plasma] (ng/mL)  
  0  
  0.25  
  0.5  
  1  
  1.5  
  2  
  3  
  4  
  6  
  8  
  12  
  18  
  24  
     
       
For a 
Default: 200g
 g rat  
[No canvas support]
p.o. dose   Series1 Series2 Series3 Series4
Dose mg/kg
Default: 5mg/kg
  mg
Ka per hr
Default: 0.5 per hr
  mg/min
F  
Default: 100%
t1/2 = hr
  min
Vd L
Default: 0.1 L
  L/kg
k per min
Default: 0.1 per min
  per hr
Cl = L/min
  L/hr