Mucociliary clearance in health and disease

Dyskinetic cilia

Diseases that affect the uniformity of cilia action (such as primary ciliary dyskinesia - PCD, a genetically inherited condition that results in abnormal ciliary function) will result in ineffective secretion transport and clearance:

  • Primary Ciliary Dyskinesia - (PCD)
  • Genetically inherited condition
  • Loss of co-ordinated ciliary action
  • Impaired secretion clearance
  • Secretion retention and repeated infections