Unit 5: Children & Squint

The five stages of retinopathy of prematurity
  • Stage 1: Demarcation line
  • Stage 2: Formation of three dimensional ridge
  • Stage 3: Fibrovascular proliferation at ridge
  • Stage 4: Partial retinal detachment
    macula on
    macula off
  • Stage 5: Total retinal detachment
  • (Stage 6: Aggressive posterior retinopathy of prematurity)

Adapted from: A reproduction by Retinopathy of prematurity, Clare M Wilson, Alistair R Fielder, BMJ 2008;337:a2648, BMJ Publishing Group Ltd.

“Plus disease” refers to characteristic vascular changes of congestion and tortuosity at the posterior pole.